Wednesday, May 26, 2010

B. pseudomallei K96243

Burkholderia Pseudomallei strain K96243 was a clinical isolate from Thailand. The genome of B. pseudomallei is 7 247 547 bp in size and the G+C content is 68.06%. It has 2 chromosome of 4 074 542 bp and 3 173 005 bp. The genome of B. pseudomallei carries many genomic islands as compared to its related organism, B. mallei, suggesting extensive horizontal transfer.

There are 3 different type III secretion systems (TTSS) are encoded on the chromosomes of this organism. Two of it are similar to plant pathogenic TTSSs, while the third is similar to the Salmonella pathogenicity island, all of which may contribute to pathogenicity. This organism also carries a number of small sequence repeats which may promoter antigenic variation, similar to what was found with the B. mallei genome.

The lineage of the B. pseudomallei is:
Bacteria > Proteobacteria > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia > Pseudomallei group > Burkholderia pseudomallei > Burkholderia pseudomallei K96243


reference:
1) http://www.ncbi.nlm.nih.gov/sites/entrez?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=178

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